ORIGINAL ARTICLE
Year : 2020  |  Volume : 22  |  Issue : 1  |  Page : 8-12

Prevalence of metabolic syndrome in HIV-infected and Non-HIV infected Nigerian children in Jos


Department of Paediatric, Jos University Teaching Hospital, University of Jos, Lamingo, Plateau State, Nigeria

Correspondence Address:
Abok Ibrahim Ishaya
Department of Pediatrics, University of Jos, Plateau State
Nigeria
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jomt.jomt_17_19

Rights and Permissions

Background: Both Human Immune-deficiency Virus (HIV) and anti-retroviral (ARV) are associated with metabolic disorder. This study compared the prevalence of metabolic syndrome (MetS) among HIV and non-HIV infected children. Methods: This was a comparative cross-sectional study of 142 HIV infected and 142 HIV non-infected children. Socio-demographic and clinical data were collected. Blood pressure, height, weight abdominal circumference were assessed using standard procedure. Fasting blood samples were collected for blood glucose and blood lipid profile. Result: The mean age at diagnosis of HIV infection was 4.9 years and 140 children were on ARVs. Cumulatively, 23.9% of the non-HIV infected children compared to 16.2% of HIV children (P = 0.11) had one component of MetS. Abdominal obesity was prevalent in 3.5% of non-HIV compared to 0% of HIV infected children; high blood pressure (HBP) was present in 8.5% of non-HIV compared to 0.7% of HIV-infected children (P < 0.001). HIV-infected children had higher prevalence of hyper-triglyceridemia compared to non-HIV (9.3% compared 3.5% respectively; P = 0.05). Cumulatively the clustering of two components of MetS was prevalent in 2.8% each of HIV-infected and non-HIV-infected children. Atherogenic lipids (low high density lipo-protein and high triglyceride) was diagnosed in 2.8% versus 0.7% of HIV infected and non-infected respectively (P = 0.18). MetS was diagnosed in 0.7% of non-HIV infected children and none of the HIV infected children. Conclusion: While both HIV and non-HIV-infected children had a high prevalence of one component of the MetS, MetS is however uncommon in our study population.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed77    
    Printed2    
    Emailed0    
    PDF Downloaded30    
    Comments [Add]    

Recommend this journal